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China Journal of Chinese Materia Medica ; (24): 1044-1047, 2007.
Artículo en Chino | WPRIM | ID: wpr-235267

RESUMEN

<p><b>OBJECTIVE</b>To study the chemical constituents of Ligularia intermedia of Shanxi.</p><p><b>METHOD</b>The compounds were isolated by column chromatography on silica gel and preparative TLC. The structures were identified by IR, MS, 1D/2DNMR spectral data and X-ray single crystal diffraction and other methods1.</p><p><b>RESULT</b>Nine compound were isolated and identified as 8beta-hydroxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (1), 8beta-methoxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (2), petasin (3), isopetasin (4), liguhodgsonal (5), ligudentatol (6), ligujapone (7), lupeol (8) and lupeol palmitate (9).</p><p><b>CONCLUSION</b>Compounds 2, 3, 4, 6, 7 and 9 were isolated from the plant for the first time.</p>


Asunto(s)
Asteraceae , Química , Conformación Molecular , Estructura Molecular , Plantas Medicinales , Química , Sesquiterpenos , Química , Estereoisomerismo
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